pizza: I'm currently losing weight but tomorrow I have a birthday to go to unfortunately at a pizza place in which all there is is deep dish pizza. Anyone know how many calories one slice of pepperoni deep dish pizza has?|||i doubt all they have is pizza. try looking at the menu online and seeing what they have that's a more healthy option. but there's probably about 400 or 500 calories in a slice. the pepperoni accounts for ALOT more fat and calories than you'd think and same with the extra cheese that a deep dish style has|||It depends on the size of the slice. For a 14" pizza, a slice will probably sit somewhere between 250 and 400 calories for deep dish. It's the quality, not quantity, of the calories you should worry about in this case. Most of the calories will be coming from long-chained fats. Really, though, you shouldn't worry too much.